Michael Arad Selected Research

Reperfusion Injury

7/2011	Rapamycin (sirolimus) protects against hypoxic damage in primary heart cultures via Na+/Ca2+ exchanger activation.
4/2008	Increased glycogen stores due to gamma-AMPK overexpression protects against ischemia and reperfusion damage.

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Michael Arad Research Topics

Disease

20	Cardiomyopathies (Cardiomyopathy) 05/2024 - 06/2003
15	Heart Failure 10/2023 - 06/2005
14	Polymorphic catecholergic ventricular tachycardia 01/2020 - 07/2007
10	Cardiac Arrhythmias (Arrythmia) 10/2023 - 07/2007
9	Cardiomegaly (Heart Hypertrophy) 10/2022 - 02/2002
9	Hypertrophy 01/2021 - 06/2003
8	Inflammation (Inflammations) 03/2024 - 01/2015
8	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 11/2019 - 02/2002
7	Glycogen Storage Disease Type IIb 10/2023 - 06/2003
7	Fibrosis (Cirrhosis) 10/2022 - 02/2002
6	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 10/2022 - 07/2014
6	Obesity 01/2022 - 01/2016
6	Diabetic Cardiomyopathies 10/2020 - 01/2017
5	Amyloidosis 03/2024 - 01/2021
5	Ventricular Tachycardia 10/2023 - 12/2013
5	Ischemia 01/2016 - 04/2005
4	Heart Diseases (Heart Disease) 10/2023 - 01/2018
4	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 10/2023 - 06/2003
4	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 08/2022 - 01/2018
4	Insulin Resistance 01/2022 - 01/2016
4	Neoplasms (Cancer) 01/2021 - 03/2007
4	Wolff-Parkinson-White Syndrome (Wolf-Parkinson-White Syndrome) 01/2018 - 02/2002
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 01/2016
3	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2021 - 01/2019
3	Left Ventricular Dysfunction 01/2015 - 03/2009
2	Pericarditis 03/2024 - 10/2022
2	Immunoglobulin Light-chain Amyloidosis 03/2024 - 02/2023
2	Disease Progression 10/2022 - 01/2016
2	Mitochondrial Diseases (Mitochondrial Disease) 05/2019 - 01/2018
2	Ventricular Premature Complexes (Premature Ventricular Contraction) 01/2019 - 12/2013
2	Fabry Disease (Fabry's Disease) 01/2019 - 01/2018
2	Protein Deficiency 01/2017 - 12/2012
2	Sudden Death 01/2017 - 03/2009
2	Hypoxia (Hypoxemia) 07/2011 - 03/2007
2	Reperfusion Injury 07/2011 - 04/2008
2	Atrioventricular Block 09/2003 - 02/2002
2	Glycogen Storage Disease (Glycogenosis) 06/2003 - 02/2002
1	Peripheral Nervous System Diseases (PNS Diseases) 03/2024
1	Paraproteinemias (Monoclonal Gammopathy) 03/2024
1	Transthyretin-Related Hereditary Amyloidosis 02/2023
1	Myocardial Infarction 02/2023
1	Carpal Tunnel Syndrome 01/2023
1	Median Neuropathy 01/2023
1	Aortic Valve Stenosis (Aortic Stenosis) 01/2023

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 03/2024 - 02/2002
9	CalsequestrinIBA 01/2020 - 07/2007
8	GlycogenIBA 01/2018 - 06/2003
7	CalciumIBA 01/2021 - 01/2009
7	AMP-Activated Protein KinasesIBA 10/2007 - 02/2002
6	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 08/2015 - 07/2007
5	DystrophinIBA 08/2022 - 01/2018
4	Amyloid (Amyloid Fibrils)IBA 03/2024 - 01/2021
4	CatecholaminesIBA 01/2021 - 11/2010
4	Sirtuin 1IBA 05/2019 - 01/2018
4	Phosphotransferases (Kinase)IBA 01/2018 - 03/2007
3	Glucose (Dextrose)FDA LinkGeneric 06/2022 - 01/2018
3	AcidsIBA 10/2020 - 01/2016
3	PPAR gammaIBA 10/2020 - 12/2018
3	Angiotensin IIIBA 05/2019 - 01/2018
3	LeptinIBA 12/2018 - 10/2007
3	ConnectinIBA 01/2018 - 06/2012
2	CytokinesIBA 03/2024 - 01/2015
2	Prealbumin (Transthyretin)IBA 03/2024 - 01/2023
2	pro-brain natriuretic peptide (1-76)IBA 10/2023 - 05/2008
2	EnzymesIBA 10/2023 - 10/2007
2	Adenosine Triphosphate (ATP)IBA 10/2023 - 03/2007
2	Sirolimus (Rapamycin)FDA Link 10/2022 - 07/2011
2	AdipokinesIBA 01/2022 - 08/2017
2	Adrenergic Agents (Adrenergic Drugs)IBA 01/2021 - 08/2014
2	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 10/2020 - 08/2017
2	20-hydroxy-5,8,11,14-eicosatetraenoic acidIBA 10/2020 - 01/2016
2	Adenosine Monophosphate (AMP)IBA 01/2018 - 03/2007
2	AngiotensinsIBA 01/2018 - 01/2017
2	Lysosomal Membrane ProteinsIBA 09/2017 - 03/2009
2	RyanodineIBA 08/2015 - 12/2012
2	Propranolol (Inderal)FDA LinkGeneric 08/2014 - 11/2010
2	Epinephrine (Adrenaline)FDA LinkGeneric 08/2014 - 12/2013
2	Verapamil (Calan)FDA LinkGeneric 03/2011 - 11/2010
2	Procainamide (Procan)FDA LinkGeneric 11/2010 - 09/2003
2	Adenosine (Adenocard)FDA LinkGeneric 01/2010 - 09/2003
1	Interleukin-1alpha (Interleukin 1 alpha)IBA 03/2024
1	SuspensionsIBA 03/2024
1	rilonacept FDA Link 03/2024
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 10/2023
1	Amyloidogenic ProteinsIBA 02/2023
1	Spironolactone (Aldactone)FDA LinkGeneric 01/2023
1	Ramipril (Altace)FDA LinkGeneric 01/2023
1	Proteasome Endopeptidase Complex (Proteasome)IBA 10/2022
1	BNT162 VaccineIBA 10/2022

Therapy/Procedure

20	Therapeutics 05/2024 - 09/2003
6	Heart Transplantation (Grafting, Heart) 10/2023 - 03/2009
5	Caloric Restriction 10/2022 - 01/2017
2	Exercise Therapy (Therapy, Exercise) 11/2019 - 01/2017
2	Enzyme Replacement Therapy 01/2019 - 11/2015
2	Peritoneal Dialysis 01/2015 - 01/2013
1	Duration of Therapy 03/2024
1	Heart-Assist Devices 02/2023
1	Transplantation 02/2023
1	Denervation 01/2023
1	Transcatheter Aortic Valve Replacement 01/2023